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Thursday, September 18, 2014

সিপ্রোফ্লক্সাসিন




সিপ্রোফ্লক্সাসিন একটি সিনথেটিক কেমোথেরাপিউটিকএজেন্ট যা জীবনহরনকারি কিছু ক্ষতিকারক ব্যাকটেরিয়াল ক্ষত নিরাময়ের জন্য ব্যবহৃত হয়।ফ্লুরোকুইনোলনপরিবারের ১টি ব্যাকটেরিয়া রোধি ঔষধ হিসেবে এর ব্যবহার।২য় প্রজন্মের এই এনটিবায়োটিক সারা বিশ্বে ৩০০ রও বেশী কোম্পানি এটি বিভিন্ন নামে এটি বাজারজাত করছে।বাংলাদেশে সিপ্রোসিন, সারভিনাপ্রক্স, ফ্লনটিন, সিপ্রো, কেপ্রন ইত্যাদি নামে পাওয়া যায়।এর ২৫০ মিলিগ্রাম, ৫০০ মি.গ্রা.ও ৭৫০ মি.গ্রা. ৩ মাত্রার ট্যাবলেট, সিরাপ,ইনজেকশন ফরমে পাওয়া যায়। পশুর জন্যওএটি পাওয়া যায়। ও

Tuesday, September 16, 2014

Burna


Burna<sup>®</sup>


Burna®
Silver Sulfadiazine
Antibacterial (Topical Preparations)

Indication : The topical prophylaxis against bacterial colonization and infection in burn wounds.

Dosage & Administration: Once to twice daily to a thickness of approximately 1/16 inches or 1.5 mm.

Preparation: Each pack has a laminated tube containing 25 gram cream

Oxifun®


Oxifun<sup>®</sup>


Oxifun®

Oxiconazole
Fungicides (Topical Preparations)

Indication : Indicated for the topical treatment of the following dermal infections: tinea pedis, tinea cruris, and tinea corporis due to Trichophyton rubrum, Trichophyton mentagrophytes, or Epidermophyton floccosum. Oxifun® Cream is indicated for the topical treatment of tinea (pityriasis) versicolor due to Malassezia furfur.

Dosage & Administration : Oxifun® Cream should be applied to affected and immediately surrounding areas once to twice daily in patients with tinea pedis, tinea corporis, or tineacruris. Oxifun®Cream should be applied once daily in the treatment of tinea (pityriasis) versicolor. Tinea corporis, tinea cruris, and tinea (pityriasis) versicolor should be treated for 2 weeks and tinea pedis for 1 month to reduce the possibility of recurrence.

Preparation: Oxifun® Cream: Each pack contains 10 gm cream in a laminated tube.

Emolent Cream

Emolent<sup>TM</sup> Cream



EmolentTM Cream


Light liquid paraffin & White soft paraffin
Anti-itching and Moisturizer (Topical Preparations)
Indication : EmolentTM Cream is indicated for the treatment of dry skin conditions.

Dosage & Administration : Light liquid paraffin and White soft paraffin cream is used as often as required. Apply to the affected area and rub in well. It is specially effective after washing body areas because the sebum content of the stratum corneum may be depleted after washing resulting in excessive moisture loss.

Preparation: Each laminated tube contains 25 gm cream.

POVISEP CREAM



Povisep Cream

  • Therapeutic Group
  • : ANTISEPTICS

  • Generic Name
  • : Povidone - Iodine 6%
  • Product Name
  • : Povisep Cream



  • Product Type
  • :

  • Product Strength
  • : 60mg/mL

  • Product Pack Size : 5g ,25g
Indication:
Povisep Cream



Amodis IV








Amodis IV Infusion®
Metronidazole
Antiamoebics & Antianaerobes (Systemic Antifungal, Antiviral and Antiprotozoal Agents)
Preparation: Amodis® 500 IV: Each box contains 1 bag of 100 ml solution of Metronidazole for intravenous infusion.




http://www.squarepharma.com.bd/products-details.php?pid=293

Metronidazole Uses, Dosage & Side Effects

Metronidazole                                                    

Generic Name: metronidazole ( me troe NI da zole )

Metronidazole is an antibiotic. It fights bacteria in your body.
Metronidazole is used to treat bacterial infections of the vagina, stomach, skin, joints, and respiratory tract. This medication will not treat a vaginal yeast infection.
Metronidazole may also be used for purposes not listed in this medication guide.

Important information


Take metronidazole for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Metronidazole will not treat a viral infection such as the common cold or flu. Do not drink alcohol while you are taking metronidazole and for at least 3 days after you stop taking it. You may have unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.

Before taking this medicine

You should not use this medication if you are allergic to metronidazole, or if you are in the first trimester of pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
Before taking metronidazole, tell your doctor if you are allergic to any drugs, or if you have:
  • liver disease;
  • a stomach or intestinal disease such as Crohn's disease;
  • a blood cell disorder such as anemia (lack of red blood cells) or leukopenia (lack of white blood cells);
  • epilepsy or other seizure disorder; or
  • nerve disorders.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.
Metronidazole can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Metronidazole Side Effects

More common
  • Agitation
  • back pain
  • blindness
  • blurred vision
  • burning, numbness, tingling, or painful sensations in the hands or feet
  • changes in speech patterns
  • confusion
  • convulsions
  • decreased vision
  • depression
  • dizziness
  • drowsiness
  • eye pain
  • fever
  • hallucinations
  • headache
  • irritability
  • lack of coordination
  • nausea
  • seizures
  • shakiness and unsteady walk
  • slurred speech
  • stiff neck or back
  • trouble speaking
  • unsteadiness, trembling, or other problems with muscle control or coordination
  • unusual tiredness or weakness
  • vomiting
  • weakness in the arms, hands, legs, or feet
Less common
  • Black, tarry stools
  • blood in the urine or stools
  • body aches or pain
  • chills
  • clumsiness or unsteadiness
  • difficulty with breathing
  • ear congestion
  • feeling of pelvic pressure
  • frequent or painful urination
  • loss of voice
  • nasal congestion
  • pinpoint red spots on the skin
  • runny nose
  • skin rash, hives, redness, or itching
  • sneezing
  • stomach and back pain (severe)
  • unusual bleeding or bruising
  • vaginal irritation, discharge, or dryness not present before taking the medicine
Rare
  • Bleeding gums
  • bloating
  • chest pain
  • constipation
  • cough
  • dark-colored urine
  • fast heartbeat
  • indigestion
  • loss of appetite
  • painful or difficult urination
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • swollen glands
  • yellow eyes or skin
Incidence not known
  • Blistering, peeling, or loosening of the skin
  • bloody or cloudy urine
  • burning while urinating
  • continuing diarrhea
  • continuing stomach pain
  • diarrhea
  • feeling of warmth
  • increased volume of pale, dilute urine
  • joint or muscle pain
  • loss of bladder control
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • redness of the face, neck, arms, and occasionally, upper chest
  • redness of the skin

How should I take metronidazole?

Take metronidazole exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Take the extended-release metronidazole tablet (Flagyl ER) on an empty stomach, at least 1 hour before or 2 hours after eating a meal. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time. Take metronidazole for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Metronidazole will not treat a viral infection such as the common cold or flu.
To be sure metronidazole is not causing harmful effects, your blood may need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.
This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using metronidazole.
Store metronidazole at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include nausea, vomiting, dizziness, loss of balance or coordination, numbness and tingling, or seizures (convulsions).

What should I avoid?

Do not drink alcohol while you are taking metronidazole and for at least 3 days after you stop taking it. You may have unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.
Check the labels of any medicines or food products you use to make sure they do not contain alcohol.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking metronidazole and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Metronidazole side effects

Get emergency medical help if you have any of these signs of an allergic reaction to metronidazole: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
  • numbness or tingling in your hands or feet;
  • white patches or sores inside your mouth or on your lips;
  • pain or burning when you urinate;
  • diarrhea that is watery or bloody;
  • vision problems, pain behind your eyes;
  • trouble concentrating, slurred speech, mood or behavior changes, tremors, muscle twitching, seizure (convulsions);
  • fever, chills, muscle pain, confusion, headache, sore throat, neck stiffness, increased sensitivity to light, drowsiness, nausea and vomiting; or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Less serious metronidazole side effects may include:
  • stomach pain, diarrhea;
  • dizziness, loss of balance;
  • vaginal itching or discharge;
  • dry mouth or unpleasant metallic taste;
  • cough, sneezing, runny or stuffy nose; or
  • swollen or sore tongue.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)

What other drugs will affect metronidazole?

Tell your doctor about all other medicines you use, especially:
  • cimetidine (Tagamet);
  • seizure medication such as phenytoin (Dilantin) or phenobarbital (Luminal, Solfoton);
  • a blood thinner such as warfarin (Coumadin, Jantoven);
  • lithium (Lithobid, Eskalith, others); or
  • disulfiram (Antabuse).
This list is not complete and other drugs may interact with metronidazole. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Amodis Tab. ..... Made by square



Amodis®


Metronidazole



Antiamoebics & Antianaerobes (Systemic Antifungal, Antiviral and Antiprotozoal Agents)
Indication: All forms of amoebiasis (intestinal and extra-intestinal disease including liver abscess and that of symptomless cyst passers)
Trichomoniasis
Giardiasis Bacterial vaginosis
Acute ulcerative gingivitis
Anaerobic infections including septicaemia, bacteraemia, peritonitis, brain abscess, necrotising pneumonia, osteomyelitis, puerperal sepsis, pelvic abscess, pelvic cellulitis etc.
Anaerobically-infected leg ulcers and pressure sores Acute dental infections (e.g. acute pericoronitis and acute apical infections)
Surgical prophylaxis (prevention of postoperative infections due to anaerobic bacteria, particularly species of bacteroides and anaerobic streptococci
Chronic symptomatic peptic ulcer disease (as an agent









Napa..... Made by Beximco pharma



Napa


( Paracetamol )

Napa® is an analgesic & antipyretic used for the fast and effective relief of pain & fever and discomfort associated with headache, period pain, colds and flu, tension headache, backache and muscular aches. It is the safest drug of choice in pregnancy and lactation. It is  also suitable for cardiovascular risk patients, peptic ulcer patients, asthmatics who are sensitive to aspirin and non-steroidal anti-inflammatory drugs (NSAIDs). It is available in 12 different strengths of different dosage forms such as tablet, syrup, suspension, paediatric drops and suppository.

The #1 choice in pain & fever
Napa® has gained millions of physicians' trust and confidence and thereby became the number one selling brand by volume in Bangladesh pharma market (according to IMS 4th Quarter, 2005). Napa® is highly effective in relieving pain and fever. It has an excellent safety and efficacy profile. Napa® is now available in 12 different forms. It is one of the most successful brands in this decade in Bangladesh.

 NAPA Tablet
  • Disintegrates in only 19 seconds & gives prompt relief from fever & pain
  • Napa Extra relieves high fever quickly & efficiently and also supply energy to body during pain & fever
  • Napa DT offers modern technology of dispersible formulation that ensures quick onset of action

NAPA Syrup
  • 50 ml, 60 ml & 100 ml Syrup  Quick absorption ensures faster relief from fever & pain
  • Ensures precise dosing

Napa Suppository
  • 125 mg, 250 mg & 500 mg Paracetamol The right dosage forms for pediatric & geriatric patients
  • Avoid GI irritation
  • An excellent choice when oral feeding is restricted
  • For unconscious, vomiting & mentally retarded patients

Napa Suspension
  • 50 ml & 60 ml Suspension When patients desire a different taste

Napa Drops
  • Pediatric Drops 15ml Strawberry flavored
  • Superb test
  • Concentrated formula for easy dosing





Paracetamol ....Made by Biopharma



ProductGeneric NameStrengthPack Size
 
ACETA 120mg /5ml  Paracetamol BP 120mg /5ml 60ml
ACETA 120mg/5ml  Paracetamol BP 120mg/5ml 60ml
ACETA 500mg  Paracetamol BP 500mg 20x10s
ACETA 80mg/ml  Paracetamol BP 80mg/ml 15ml
ACETA-X 500mg+65mg  Paracetamol BP+Caffein BP 500mg+65mg 10x10s


Ace



Ace®

Paracetamol
Non-narcotic analgesic (CNS Preparations)


Indication: Fever, headache, toothache, earache, bodyache, myalgia, dysmenorrhoea, neuralgia and sprains. Pain of colic, back pain, chronic pain of cancer, inflammatory pain, and post-vaccination pain and fever of children. Rheumatism and osteoarthritic pain & stiffness of joints in fingers, hips, knees, wrists, elbows, feet, ankles and top & bottom of the spine.

Dosage & Administration: Tablet : Adult 1-2 tablets every 4 to 6 hours up to a maximum of 4 g (8 tablets) daily. Children (6-12 years) 1/2 to 1 tablet 3 to 4 times daily. Syrup and Suspension Children Under 3 months: 10 mg/kg body weight (reduce to 5 mg/kg if jaundiced) 3 to 4 times daily. 3 months to below 1 year : 1/2 to 1 teaspoonful 3 to 4 times daily. 1-5 years: 1-2 teaspoonful 3 to 4 times daily. 6-12 years : 2-4 teaspoonful 3 to 4 times daily. Adults 4-8 teaspoonful 3 to 4 times daily. Paediatric Drop Children Upto 3 months: 0.5 ml (40 mg) 4 to 11 months: 1.0 ml (80 mg). 1 to 2 years: 1.5 ml (120 mg) Dose can be repeated, every 4 hours. Suppository : Suppository should be administered rectaly. Children 3 months - 1 year : 60-120 mg 4 times daily. Children below 5 years : 125-250 mg, 4 times daily. Children 6-12 years : 250-500 mg, 4 times daily. Adults and children over 12 years : 0.5 - 1 mg, 4 times daily.

Preparation: Ace® Tablet : Each box contains 500 tablets in blister pack. Ace® XR Tablet : Each box contains 100 tablets in blister pack. Ace® Syrup (60 ml) : 60 ml syrup in sealed cap PET bottle (with measuring cup). Ace® Syrup (100 ml) : 100 ml syrup in sealed cap PET bottle (with measuring cup). Ace® Suspension : 60 ml suspension in sealed cap PET bottle. Ace® Paediatric drops (15 ml): 15 ml paediatric drop in sealed cap PET bottle (with dropper). Ace®Paediatric drops (30 ml): 30 ml paediatric drop in sealed cap PET bottle (with dropper). Ace® 60 Suppository : Each box contains 10 suppositories in blister pack. Ace® 125 Suppository : Each box contains 20 suppositories in blister pack. Ace® 250 Suppository : Each box contains 20 suppositories in blister pack. Ace® 500 Suppository : Each box contains 20 suppositories in blister pack.





















Paracetamol


Renova®

Paracetamol
 Description: 
Paracetamol (Renova®) is a potent and fast acting antipyretic & mild analgesic together with some anti-inflammatory effects. Paracetamol is the most widely used popular domestic analgesic and antipyretic for adults and children with significantly less side effects at the recommended dose.

Mode of action: 
Analgesic effects are thought to be related to the inhibition of prostaglandin synthesis and antipyresis through action on the hypothalamic heat-regulating center.

Pharmacokinetics:
 Paracetamol is rapidly and completely absorbed after oral administration with peak plasma concentration occurring between 15 mins and 2 hrs after ingestion depending on the formulation. Paracetamol is well absorbed following rectal administration but the rate of absorption is slow. The mean half-life is about 2.3 hrs, with a range of 1.5-3.0 hrs. Paracetamol is extensively metabolized in the liver. Some 2-5% of a therapeutic dose of Paracetamol is excreted unchanged in the urine.

Composition:
 Renova® Tablet: Each tablet contains 500 mg Paracetamol BP. Renova® XR Tablet: Each extended release tablet contains 665 mg Paracetamol BP. Renova® Syrup: Each 5 ml contains 120 mg Paracetamol BP. Renova® Suspension: Each 5 ml contains 120 mg Paracetamol BP. Renova® Paediatric drops: Each ml contains 80 mg Paracetamol BP. Renova® 60 mg Suppository: Each suppository contains 60 mg Paracetamol BP. Renova® 125 mg Suppository: Each suppository contains 125 mg Paracetamol BP. Renova® 250 mg Suppository: Each suppository contains 250 mg Paracetamol BP. Renova® 500 mg Suppository: Each suppository contains 500 mg Paracetamol BP.

 Indications: 
Fever, common cold and influenza, headache, toothache, earache, myalgia, dysmenorrhea, neuralgia and sprains, back pain, post-operative pain, post-partum pain,  post-vaccination pain and fever of children, rheumatism and osteoarthritic pain.

Dosage & administration
Dosage form
Tablet
XR Tablet
Suspension
&
Syrup
Paediatric
drops
Paediatric
drops
Suppository

Age
Adults
Children (6-12 yrs)
Adults and children
over 12 years
Up to 3 months
3 months to 1 yr
1 to 5 yrs
6 to 12 yrs
Adults
Up to 3 months
4 to 11 months
1 to <2 yrs
2 to 3 yrs
4 to 5 yrs
Children up to
1 yrs
Children 1 to
5 yrs
Children 6 to
12 yrs
Adults

Dosing
1-2 tablets, every 4-6 hrs to a
maximum of 4 gm daily

1/2 to 1 tablet; dose may be
repeated every 4-6 hrs when
necessary

2 tablets, swallowed whole,
every 8 hours

10 mg/kg body weight (reduce to
5 mg/kg if jaundiced); dose may
be repeated every 4-6 hrs when
necessary

1/2 to 1 teaspoonful; dose may be
repeated every 4-6 hrs when
necessary

1 to 2 teaspoonful; dose may be
repeated every 4-6 hrs when
necessary

2 to 4 teaspoonful; dose may be
repeated every 4-6 hrs when
necessary

4 to 8 teaspoonful; dose may be
repeated every 4-6 hrs when
necessary

Do not exceed 4 doses in 24 hrs

40 mg (0.5 ml); dose may be
repeated every 4 hrs when
necessary
 80 mg (1 ml); dose may be repeated 
every 4 hrs when necessary
 120 mg (1.5 ml); dose may be repeated 
every 4 hrs when necessary
 160 mg (2 ml); dose may be repeated 
every 4 hrs when necessary
 240 mg (3 ml); dose may be repeated 
every 4 hrs when necessary
 Do not exceed 5 doses in 24 hrs
 60 mg as a single dose, repeated
once after 6 hrs when necessary
 125 to 250 mg; dose may be repeated 
every 6 hrs when necessary
 250 to 500 mg; dose may be repeated 
every 6 hrs when necessary
 500 mg to 1 gm; dose may be repeated 
every 6 hrs when necessary


Contraindications: 
Known sensitivity to Paracetamol.

 Side effects: Side effects are rare with nausea, vomiting, anorexia & abdominal pain; but skin rashes and acute pancreatitis are reported after prolonged use; hepatic damage and less frequently renal damage on acute overdose.

Use in pregnancy & lactation: 
Paracetamol crosses the placenta and appears in the breast milk, but this is widely used in pregnancy and lactation and no foetal adverse effects have been recorded at the recommended doses.

Precautions: 
Paracetamol should be given with care in patients with impaired renal & hepatic functions and alcohol dependence.

Drug Interactions: 
Alcohol, barbiturates, anticonvulsants and tricyclic antidepressants may increase hepatotoxicity of Paracetamol, particularly after an overdose. The speed of absorption of Paracetamol may be increased by metoclopramide or domperidone. The anticoagulant effect of warfarine and other coumarins may be enhanced by prolonged regular use of Paracetamol with increased risk of bleeding.

Storage: 
Store in a cool and dry place, protected from light.

Packaging:
Renova® Tablet: Each carton contains 10X25 tablets in blister pack.
Renova® XR Tablet: Each carton contains 10X10 tablets in blister pack.
Renova® Syrup: Each carton contains a bottle having 60 ml syrup.
Renova® Suspension: Each carton contains a bottle having 60 ml suspension.
Renova® Paediatric drops: Each carton contains a bottle having 15 ml
Paediatric drops.
Renova® 60 mg Suppository: Each carton contains 5X2 suppositories in blister pack.
Renova® 125 mg Suppository:           Each carton contains 5X2 suppositories in blister pack.
Renova® 250 mg Suppository:           Each carton contains 5X2 suppositories in blister pack.

Renova® 500 mg Suppository: Each carton contains 5X2 suppositories in blister pack.

Afrooooooooooooooooooooooooooooooooooooooooooooooz

Drug Index

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