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Tuesday, September 2, 2014

Skin Care




Beximco Pharma's robust product line in the skin care category offers easy and convenient solution to wide range of skin diseases like fungal and bacterial infections, eczema, atopic dermatitis, other inflammatory skin diseases requiring corticosteroid therapy, acne, psoriasis, and various other dry skin problems.

Atolimus

( Tacrolimus ointment )
Atolimus® ointment contains Tacrolimus, a steroid-free topical calcineurin inhibitor, works by inhibiting T-lymphocyte activation. Atolimus® ointment is indicated for the short-term & non-continuous chronic treatment of moderate to severe atopic dermatitis, unresponsive eczema and inflammatory dermatoses in both adults & children (not less than two years of age). It is for topical dermatologic use, twice daily to the affected areas, is very effective for atopic dermatitis and severe eczema.

Burnsil

( Silver Sulfadiazine Cream )
Burnsil® is a local chemotherapeutic agent for prevention and treatment of burn wound infections. Silver Sulfadiazine disintegrates in the burn wound and thereby causing a slow and sustained release of silver ions. Silver ions bind to bacterial deoxyribonucleic acid, thus inhibiting the growth and multiplication of bacterial cells without affecting the cells of the skin and subcutaneous tissue. Burnsil® cream has a broad antibacterial spectrum including virtually all microbial species likely to infect the burn wound: Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, strains of Proteus and Klebsiella; it is also effective against Candida albicans and other fungi. Burnsil® (Silver Sulfadiazine) penetrates into the necrotic tissue and exudate. This effect is very important in view of the fact that systemic antibiotics are not effective against the bacterial flora of vascular burn necrosis.

Candoral oral gel

( Miconazole 2 % w/w)

Candoral® oral gel is the preparation of Miconazole. It is a synthetic imidazole anti-fungal agent with a broad spectrum of activity against pathogenic fungi (including yeast and dermatophytes) and gram-positive bacteria (Staphylococcus and Streptococcus spp). Its activity is based on the inhibition of the ergosterol (principle component of fungi cell membrane) biosynthesis in fungi and the change in the composition of the lipid components in the membrane, resulting in fungal cell necrosis. Candoral® oral gel is a preparation of  indicated to treat and prevent  oral candidiasis in babies and in other age groups, nipple & breast candidiasis of lactating mother and super infections due to Gram-positive bacteria. It is also indicated in prophylactic management of patients at high risk from opportunistic fungal infections.

Cosmotrin

( Tretinoin Cream )
Cosmotrin® cream is a topical anti-acne preparation containing Tretinoin which stimulates mitotic activity and increases turnover of follicular epithelial cells, causing extrusion of the comedones, papules and pustules. It is indicated for topical application in the treatment of acne vulgaris in which comedones, papules and pustules predominate.

Ecotrim

( Econazole Nitrate and Triamcinolone Acetonide Cream )
Econazole Nitrate is a broad spectrum antifungal agent. It is effective against various dermatophytes, yeasts and moulds. Moreover, it has activity against gram positive bacteria. Triamcinolone Acetonide is a potent corticosteroid with antiinflammatory,antipruritic and antiallergic activity. Ecotrim® is indicated for dermatomycosis caused by dermatophytol yeast and fungus with clear inflammatory and allergic symptoms such as various eczematos mycosis, diaper dermatitis, eczema marzenetum, intertrigo, follicolitis, tricophytica and cycosis barbi. Ecotrim ® is also indicated for the treatment of mycosis present in various folds of the body.

Eukrim

(Cream Urea 10% BP)

Eukrim® is bacteriostatic, bactericidal, fungistatic, proteolytic, hygroscopic and has mild local anesthetic properties. These actions are dose dependent. Most of its therapeutic applications depend on its hygroscopic properties. Eukrim® is applied topically as a cream. The moisturizing effect of Eukrim® may be enhanced by applying the cream to the skin while it is still moist after washing or bathing.

Exovate

(Clobetasol Propionate 0.05% w/w Cream/Ointment)

Clobetasol Propionate is a very active topical corticosteroid which is of particular value when used in short courses for the treatment of more resistant dermatoses such as psoriasis (excluding widespread plaque psoriasis), recalcitrant eczemas and other conditions which do not respond satisfactorily to less active steroids.

A small quantity should be applied to the affected area once or twice daily until improvement occurs. Therapy should be discontinued when control is achieved. It is recommended that treatment should not be continued for more than two or four weeks without the patients’ condition being reviewed.

Exovate N

( Clobetasol Propionate, Neomycin Sulfate and Nystatin Cream )
Clobetasol Propionate is a highly active corticosteroid with topical anti-inflammatory activity. The major effect of Clobetasol Propionate on skin is a non-specific antiinflammatory response, partially due to vasoconstriction and decrease in collagen synthesis. The use of Nystatin in the local treatment of candidal infections of the skin and of Neomycin as a broad-spectrum antibiotic is well known.Exovate ®N cream is indicated in more resistant dermatoses such as recalcitrant eczemas and psoriasis (excluding widespread plaque psoriasis) where secondary bacterial or candidal infection is present, suspected or likely to occur, as when using occlusive dressings.

Fungistin

( Nystatin Suspension )
Fungistin® is a preparation of Nystatin. It is used to treat fungal infections of the skin, mouth, vagina, and intestinal tract. Fungistin® suspension usually is used three to five times a day for mouth infections and three times a day for intestinal infections.

Furasep

( Nitrofurazone Cream )
Furasep® is broad spectrum topical antibacterial agent. It is indicated for the infectious conditions of the skin such as burns, wounds, wounds, ulcers, skin infections and skin grafting. It is available as cream preparation.

Fusidic Plus

( Sodium Fusidate and Hydrocortisone Ointment )
Fusidic® Plus is an excellent combination of antibacterial and anti-inflammatory drugs which is indicated in eczema and dermatitis with secondary bacterial infections, including atopic eczema, primary dermatitis and allergic and seborrhoeic dermatitis where the organisms are known to be or believed to be sensitive to Fusidic acid.

Gentocep

( Gentamicin cream )
Gentosep® is Gentamicin Sulfate which is a water soluble antibiotic of the aminoglycoside group, active against a wide variety of pathogenic gram-positive and gram-negative microorganisms.Gentosep® cream is indicated for the topical treatment of the primary and secondary bacterial infections of the skin caused by the organisms sensitive to Gentamicin. Gentosep may clear infections that have not responded to other topical antibiotics.

Limogel

( Lysine hydrochloride 150 mg/gm ointment)

Limogel® is a preparation of Lysine hydrochloride. It is an essential amino acid & soluble in water. It promotes healing of wounds by active and controlled regeneration of cells. It also protects the wounds against common organisms. It plays an important role in the formation of collagen, a substance important for bones and connective tissues including skin, tendon, and cartilage. Lysine is important for proper growth, and it plays an essential role in the production of carnitine, a nutrient responsible for converting fatty acids into energy and helping to lower cholesterol. It is indicated in the prevention of infection in cuts, wounds abrasions, surgical incisions, burns, advance chronic wounds and infected traumatic lesions.

Neosten

( Clotrimazole Cream )
Neosten® has broad-spectrum antifungal action on dermatophytes, yeasts and other fungi. The mentioned dermatomycoses includes interdigital mycoses (e.g. athletes, foot), paronychias (associated with nail mycoses), mycoses in skin folds, candida vulvitis, candida balanitis, pityriasis versicolor and erythrasma. Neosten® cream is odorless, can be washed off, does not stain and when applied topically Neosten® cream is well tolerated.

Neosten HC

(Clotrimazole & Hydrocortisone Cream)
Clotrimazole is a broad-spectrum antifungal agent active on dermatophytes, yeasts and other fungi. Hydrocortisone is a glucocorticoid with both glucocorticoid and to a lesser extent mineralocorticoid activity. Hydrocortisone is used for replacement therapy in adrenocortical insufficiency.

Neosten VT

( Clotrimazole Vaginal Tablet )
Neosten® VT nas broad-spectrum antimycotic with fungicidal and trichomonacidal action.Neosten® VT acts reliably on dermatophytes, yeasts and other fungi. It is also effective against Trichomonas vaginalis and Gram-positive microorganisms (streptococci/staphylococci) and Gram-negative microorganisms (Bacteroides/Haemophilus vaginalis).Absorption Neosten® VT through the vaginal skin is very good and devoid of systemic effects. Local tolerance of Neosten® vaginal tablets is generally good.

Noscab

( Permethrin Cream )
Noscab® (Permethrin) Cream is a topical scabicidal agent for the treatment of infestation with Sarcoptes scabiei (scabies). Permethrin is a photo stable synthetic pyrethroid that possesses a broad spectrum of insecticidal activity including lice, ticks, fleas, mites and other arthropods and is generally rated as the safest insecticide because of its low primary toxicity.

Omastin

( Fluconazole Capsule/Suspension )
Omastin® (Fluconazole) is a triazole antifungal agent. It is a potent and selective inhibitor of fungal cytochrome P-450 dependent enzymes necessary for the synthesis of ergosterol.The daily dose of Omastin®should be based on the nature and severity of the fungal infection. Treatment should be continued until clinical parameters or laboratory tests indicate that active fungal infection has subsided. An inadequate period of treatment may lead to recurrence of active infection. Immuno compromised patients.

Omastin Duo

(Fluconazole 150 mg Capsule and Clotrimazole 1% w/w Cream)

Omastin Duo® combines a single oral Omastin® 150 mg capsule to treat the vaginal thrush and a Neosten®cream to relieve the external itching and soreness induced by the infection. Vaginal thrush is a very common condition. It is estimated that around 75% of all adult women will have at least one episode during their lifetime. The symptoms of thrush can be unpleasant and should always be treated promptly. The single oral Fluconazole 150 mg capsule treats vaginal thrush effectively and the topical Clotrimazole 1% w/w cream heals the symptoms promptly like itching, burning etc.


Omastin IV

(Fluconazole USP 2mg/ml)

IV Infusion

Omastin IV is the intravenous infusion formulation of Fluconazole, a synthetic triazole antifungal agents, It is  a sterile clear, colorless no-pyrogenic isotonic  solution intended for  intravenous use. It is available as 200mg/100ml infusion.

Omastin IV is suitable for  Invasive candidal infections (including candidaemia and disseminated candidiasis) , Cryptococcal infections (including meningitis), Mucosal Candidiasis , Prevention of relapse of cryptococcal meningitis in HIV-infected patients .It  also ensures result in prevention of fungal infection in patients with malignancy, AIDS, in intensive care units and patients on immunosuppressive drugs.
  • Excellent  front-line drug to treat Candidemia
  • Superior treatment option for infants with severe fungal infections.


Q-Rash

( Zinc Oxide Ointment )
Q-Rash® is a diaper Rash Ointment.It is indicated to treat or prevent skin irritations (e.g., burns,bed sore, cuts, poison ivy, diaper rash).It protects chafed skin due to diaper rash and helps seal out wetness.

Soritene

( Tazarotene )
Tazarotene is a retinoid prodrug which is converted to its active form, the cognate carboxylic acid of tazarotene, by rapid deesterification. In cell culture and in vitro models of skin, tazarotene suppresses expression of MRPα, a marker of inflammation present in the epidermis of psoriasis patients at high levels. In human keratinocyte cultures, it inhibits cornified envelope formation, whose build-up is an element of the psoriatic scale.Tazarotene is used to treat plaque psoriasis of the skin. It also works to treat acne on the face.

Tenafin

( Butenafine Hydrochloride cream )
Tenafin ® (Butenafine Hydrochloride) is a broad-spectrum antifungal agent. Butenafine Hydrochloride is hypothesized to act by inhibiting the epoxidation of squalene, thus blocking the biosynthesis of ergosterol, an essential component of fungal cell membranes. Tenafin ® (Butenafine Hydrochloride) cream is indicated for the topical treatment of the following superficial dermatophytosis: interdigital tinea pedis (athlete's foot), tinea corporis (ringworm) and tinea cruris (jock itch) due to E. floccosum, T. mentagrophytes, T. rubrum, and T. tonsurans. In the treatment of interdigital tinea pedis, Tenafin ® should be applied twice daily for 7 days or once daily for 4 weeks. Patients with tinea corporis or tinea cruris should apply Tenafin ® once daily for two weeks.

Terbex

( Terbinafine Hydrochloride Tablet, Cream )
Terbex® is a preparation of Terbinafine hydrochloride. Terbinafine is an allylamine with a range of antifungal activity. It is fungicidal against dermatophytes, moulds and certain dimorphic fungi. Terbinafine is either fungicidal or fungistatic against yeasts, depending on the species. Terbinafine interferes with fungal ergosterol biosynthesis by inhibiting squalene epoxidase in the fungal cell membrane at an early stage. This leads to a deficiency in ergosterol and to intracellular accumulation of squalene, resulting in fungal cell death. Terbex®cream is indicated for the treatment of the following dermatological infections: interdigital tinea pedis (Athlete's foot), tinea cruris (jock itch) or tinea corporis (ring worm) due to susceptible organisms and planter tinea pedis (mocasin type) due to Trichophyton spp. Terbex® tablet is indicated for the treatment of onychomycosis of the toe nail or finger nail due to dermatophytes and also by non-dermatophyte fungi.





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